CD BioSciences has been a trusted biotechnology company and our services in bio-3D printing have been well-received by our customers. The team of experts from CD BioSciences provides various types of in vitro model construction services based on the high-resolution 3Dmicroflu™ technology platform, covering almost all aspects of life science research. Here, the advantages and applications of the 3Dmicroflu™ technology platform for building skin aging models are demonstrated below.
Aging of the skin is accompanied by aging damage to skin functions, which reduces the skin's ability to protect and regulate the body. At this time, the skin is unable to adapt to changes in the internal and external environment and changes in overall appearance such as color, shape, and texture. The aging of skin is divided into endogenous aging and exogenous aging. On the one hand, endogenous aging is the natural aging of the skin with age. It is manifested by the whitening of the skin, the appearance of fine wrinkles, loss of elasticity, and sagging of the skin. On the other hand, the most important cause of exogenous aging is photoaging caused by sunlight. It is manifested as wrinkles, skin laxity, roughness, pigmentation spots formation, etc.
Skin aging models are an important tool for the study of skin aging mechanisms, methods to delay aging, and the study of specific diseases such as progeria. The construction of skin aging models that can truly reflect the physiological state is important for the study of related mechanisms and therapeutic methods. Here, CD BioSciences offers a high-resolution 3D printing technology platform called 3Dmicroflu™ for designing and customizing personalized models of skin in various states (e.g., aging or young).
Aging is the most common natural physiological phenomenon and something that researchers try to overcome and delay. The current research on skin aging mainly includes the study of aging mechanism, delayed aging and the mechanism of specific disease progeria. All the above studies need to be realized by in vitro constructed aging models. Here, CD BioSciences is used for a series of studies related to skin aging through a high-resolution bio-3D printing 3Dmicroflu™ technology platform.
Fig. 1. The general process of 3Dmicroflu™ technology platform in applying to skin aging model construction.
In addition to skin aging models, 3Dmicroflu™ technology platform is also capable of constructing normal skin as we can see in the figure above. Structurally, the skin models printed by the technology platform have a bilayer skin structure with epidermal and dermal layers. Both the aging and young skin models offered by 3Dmicroflu™ technology platform are designed to reflect as realistically as possible the skin state under physiological conditions.
3Dmicroflu™ technology platform enables high-resolution printing of aging skin, providing analytical and screening tools for the study of the rare disease progeria and the study of delayed aging. The aging skin models created by 3Dmicroflu™ technology platform will have highly similar structure and function to human skin.
Normal skin models are relatively simpler and easier to construct compared to aging disease models. Normal skin models are mainly used for skin growth and development mechanisms, skin absorption testing of applied drugs, and cosmetic effect testing.
When your experimental project requires the printing of skin aging models, our high-throughput technology platform will be your best choice. If you are interested in 3Dmicroflu™-based vascular models or have a need for custom skin aging models of your experimental projects, please feel free to contact us for customization services. All services are available on a 24/7/365 basis.