Physical Crosslinking Bioinks Customization Services
CD BioSciences is a biotechnology company that provides a high resolution 3D printing technology platform called 3Dmicroflu for biological 3D printing. In addition, we also provide high quality bioinks and bioink customization services suitable for all types of 3D printers. If you don't find the bioink which can meet your project needs in our product range, please contact us now for expert customization services. Below you will find an overview of CD BioSciences' physical crosslinking-based bioinks customization services.
Fig. 1. Schematic diagram of polymer cross-linking based on a series of physical methods.
3D printing bioinks are generally transformed into three-dimensional structures by cross-linking, so the cross-linking properties of the ink are what will directly affect the process of building three-dimensional structures. There are many issues to consider when designing and customizing bioinks, including print mechanical properties, physicochemical properties, and the ability to load cells. Physical crosslinking is one of the primary crosslinking methods for bioinks. As shown in the figure above, this process mainly includes some non-covalent bonding interactions such as hydrogen bonding, hydrophobic interactions, electrostatic interactions and ionic crosslinking. Currently, bioinks based on physical crosslinking have higher cell viability compared to other types of bioinks. However, one of the main problems prevailing is the weak mechanical strength and poor formability. This is usually done by introducing other materials to modulate and improve the print performance as well as the stability of the print structure.
Customized bioinks for different physical cross-linking methods at CD BioSciences
CD BioSciences has been committed to providing our customers with customization services for physical cross-linking based bioinks. We have the professional team with extensive experience in the design and customization of bioinks for bio-3D printing. The physical cross-linking bioinks customization services mainly include three aspects below.
CD BioSciences can provide you with a custom ion-crosslinked bioink service focused around balancing printability and cell viability. In addition to adjusting the mechanical properties by adjusting the crosslinker and ionic ratio, printing performance can be improved by adding other non-ionic polymers such as nanoparticles and photocrosslinkers.
CD BioSciences' dedicated team can provide you with high quality design and customization services for hydrogen bonding based cross-linked bioinks. Hydrogen bonds are mainly found between hydrogen-containing atoms and more polar atoms, and because of the weak relative forces, they need to be combined with other bioink materials. We can first select the material according to your printing needs, and then adjust the most suitable bioink formulation according to the mechanical properties and cell viability of the printed structure.
CD BioSciences is able to provide you with a professional customization service for bioinks cross-linked by host-object interaction. Bioinks based on host-guest interaction cross-linking are also generally required to be used in combination with other biomaterials. The host-guest interaction acts as a dynamic regulator in the composite ink, making the printability of the ink controllable and adjustable. Regarding the design of such bioinks, we are currently also mainly looking for composites that can meet the printing needs of our customers.
CD BioSciences has a team of professionals in the field of bioprinting to ensure a high quality and customized service for you. After you submit your inquiry or order, an expert immediately will meet with you face-to-face for one-on-one communication. After our experts fully understand your customization needs, you will receive feedback on your proposal within 5-7 days. You can also follow the progress of your bioinks customization in real time and propose new ideas to discuss with our experts at any time. During customization, as soon as we hear from you, you will get a response from our experts right now.
If you are interested in our bioinks customization services, please contact us now for exclusive services. All services are available on a 24/7/365 basis.
For research use only, not intended for any clinical use.
