CD BioSciences has been a trusted biotechnology company and our services in bio-3D printing have been well-received by our customers. The team of experts from CD BioSciences provides various types of in vitro model construction services based on the high-resolution 3Dmicroflu™ technology platform, covering almost all aspects of life science research. Here, the advantages and applications of the 3Dmicroflu™ technology platform for building complex vascular models in cardiovascular disease models are demonstrated below.
First of all, endogenous vascularization of organs and tissues constructed in vitro is necessary to maintain the functional and physiological characteristics of the model. In the case of cardiovascular disease models, the construction of various complex vascular circuit models is an even more important component. For example, atherosclerosis and hypertension require even more detail-based vascular models to be constructed. The most common cause of cardiovascular disease is coronary artery stenosis.
Blood vessels are the conduits through which living organisms transport blood and can be divided into arteries, veins and capillaries depending on the direction of transport. Arteries carry blood from the heart to all tissues of the body. Veins carry blood from the tissues back to the heart. Capillaries connect the arteries to the veins and are the main place for the exchange of substances between the blood and the tissues. Arteries and veins are connected through the heart and capillaries, and blood vessels throughout the body form closed conduits. Because the tubular structure of blood vessels is more detailed and complex compared to other physiological structures, bioprinting of vascular models has always shown a problem of low resolution.
CD BioSciences can provide you with 3Dmicroflu™ technology platform that has obvious advantages in terms of resolution for 3D bioprinting. The microfluidic-based 3D printing technology platform enables single-cell printing, which facilitates the printing of detailed structures. In the case of vascular printing, because of the high resolution of 3Dmicroflu™, the tubular structure of the blood vessels can be built in detail. And because of the high throughput of 3Dmicroflu™, there will be nearly no differences in the construction of vascular models from batch to batch.
Fig. 1. Various vessel types that 3Dmicroflu™ technology platform can be applied to build.
As shown in the picture above, 3Dmicroflu™ technology platform can play a significant role in the construction of various types of blood vessels in cardiovascular disease models where blood vessels are an essential component.
When your experimental project requires the printing of fine structures (e.g., blood vessels, valves, etc.), our high-throughput technology platform will be your best choice. If you are interested in 3Dmicroflu™-based vascular models or have a need for custom vascular models of your experimental projects, please feel free to contact us for customization services. All services are available on a 24/7/365 basis.