CD BioSciences is a biotechnology company dedicated to promoting the high resolution 3Dmicroflu™ 3D bioprinting technology platform and high quality customised bioinks that can be applied to 3D printing organ and tissue micro-models. 3Dmicroflu™ technology platform can provide you with the construction of fibrotic disease models to advance your research and drug screening in fibrotic disease mechanisms. CD BioSciences' experts with extensive experience in the field of bio-3D printing are waiting to receive your enquiry.
Tissue fibrosis is a major cause of disability and death in many diseases and plays an important role in the development and progression of disease in all major organs of the body. The main pathological change in fibrosis is an increase in fibrous connective tissue and a decrease in parenchymal cells in organ tissue. The end result of fibrosis is structural destruction, hypofunction and failure of organs. In the diagram below the process of lung injury culminating in lung fibrosis is demonstrated.
Fig. 1. Diagrammatic representation of physiologic and pathologic fibrotic response to lung injury. (Robert, M, S, et al., 2009)
When tissue cells are damaged, they all undergo a degenerative and inflammatory response. If the damage is minimal, the normal parenchymal cells surrounding the damaged cells will proliferate and repair. This repair can fully restore normal structure and function. However, if the injury is large or repeated, the regenerative capacity of the parenchymal cells surrounding the injury may be exceeded. Fibrosis is essentially a repair response to tissue damage, primarily to protect the relative integrity of the tissues and organs. If this repair response is excessive, overpowering and out of control, it can lead to fibrosis of the organ and a decline in organ function.
Here, CD BioSciences can provide you with 3Dmicroflu™ technological platform to help you with research related to fibrosis disease. As you can see above, once fibrosis has occurred, its damage will be irreversible. It is therefore of great significance to study the pathogenesis of fibrosis and to develop relevant prevention and treatment methods.
Fig. 2. Applications of 3Dmicroflu™ in the construction of fibrotic disease models.
Our experienced team of experts will communicate with you on a one-to-one basis after you place your order and provide you with in vitro fibrotic disease model construction services through 3Dmicroflu™ technology platform after knowing your project requirements. 3Dmicroflu™ allows the construction of conventional and personalized fibro-customized organ models, which are mainly applied around the following aspects.
If you are interested in our high-resolution 3Dmicroflu™ 3D bioprinting technology platform, please contact us now for professional services. All services are available on a 24/7/365 basis.